Indication & Dosage |
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| Intramuscular |
| TREATMENT OF GI SPASM ASSOCIATED WITH IRRITABLE BOWEL SYNDROME |
| Adult:
20 mg 4 times a day given only for 1-2 days. Replace with oral therapy as soon as possible. |
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| Oral |
| TREATMENT OF GI SPASM ASSOCIATED WITH IRRITABLE BOWEL SYNDROME |
| Adult:
10-20 mg tid. |
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| Oral |
| TREATMENT OF GI SPASM ASSOCIATED WITH IRRITABLE BOWEL SYNDROME |
| Child:
2-12 yr: 10 mg tid; 6 mth-2 yr: 5-10 mg 3-4 times daily. |
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| Administration |
dicycloverine: May be taken with or without food. (May be taken before or after meals.)
dicyclomine: May be taken with or without food. (May be taken before or after meals.) |
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| Precautions |
Hepatic or renal disease, urinary retention, paralytic ileus, hyperthyroidism, hypertension, congestive heart failure, cardiac tachyarrhythmia, children, elderly, pregnancy. |
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Potentially Life-threatening
Adverse Drug Reactions |
Difficulty in accommodation, exacerbation of glaucoma; tachycardia, palpitations, arrhythmias; urinary retention; restlessness; confusion, excitement, hallucination and delirium. |
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| Adverse Drug Reactions |
Respiratory arrest in infants <10 wk. |
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| Interactions |
Antagonise the effect of drugs that affect GI motility e.g. metoclopramide. Absorption affected by concurrent admin with antacids. |
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